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Relationship between Copper, Zinc, and Copper-to-Zinc Ratio in Hair and Severity of Coronary Artery Disease according to the SYNTAX Scores

cris.lastimport.scopus2025-06-09T03:45:20Z
cris.virtual.author-orcid0000-3123-4235-3464
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid21108330-fab7-498e-9feb-971b6d4ae57d
cris.virtualsource.author-orcid60eb5b5c-d11e-4105-8fea-35c513b2f4a6
dc.affiliationWojskowa Akademia Techniczna
dc.contributor.authorPiotrowski, Zbigniew
dc.contributor.authorBajda, Artur
dc.contributor.editorJaniszewski, Hubert
dc.date.accessioned2023-12-19T21:00:09Z
dc.date.available2023-12-19T21:00:09Z
dc.date.issued2023
dc.description.abstract<jats:p>Coronary artery disease (CAD) continues to be a foremost contributor to global mortality, and the quest for modifiable risk factors could improve prophylactic strategies. Recent studies suggest a significant role of zinc (Zn) and copper (Cu) deficiency in atheromatous plaque formation. Furthermore, hair was previously described as a valuable source of information on elemental burden during the 6–8 week period before sampling. The aim of this study was to investigate the possibility of correlation between the extent of CAD evaluated with the SYNergy Between PCI With TAXUS and the Cardiac Surgery (SYNTAX) score with Cu and Zn content in hair samples, as well as with the Cu/Zn ratio in a cohort of 130 patients. Our findings describe a statistically significant inverse correlation between Cu content and the Cu/Zn ratio in hair samples and the extent of CAD. In contrast, no significant correlation was found between Zn content and the extent of CAD. Considering the scarcity of existing data on the subject, the analysis of hair samples could yield a novel insight into elemental deficiencies and their potential influence on CAD extent.</jats:p>
dc.description.versionfinal_author
dc.identifier.doi10.3390/biology12111407
dc.identifier.isbn978-23123123
dc.identifier.issn2079-7737
dc.identifier.urihttps://dspace-demo.pcgacademia.eu/handle/123456789/100
dc.languagepl
dc.pbn.affiliationinformatyka
dc.pbn.affiliationinformatyka
dc.publisher.ministerialWAT
dc.relation.projectMobilny system dezynfekcyjny do zabezpieczenia medycznego Sił Zbrojnych RP w przeciwdziałaniu SARS-CoV-2
dc.rights.questionYes_rights
dc.titleRelationship between Copper, Zinc, and Copper-to-Zinc Ratio in Hair and Severity of Coronary Artery Disease according to the SYNTAX Scores
dc.title.journalBiology
dc.typeMonography
dspace.entity.typePublication
oaire.citation.issue11
oaire.citation.volume12
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